Instruments

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MR Solutions 3T

3T MRI

$150.00/hour*




The 3 Tesla Magnetic Resonance Imaging system is a compact cost-effective scanner offering high-throughput scanning of mice and rats. This scanner offers the next-generation green magnet technology with the superconducting magnet chilled using a cryogen-free system. A full array of proton radiofrequency coils is available including mouse brain and body as well as rat brain and body coils. Abdominal imaging is accomplished using a fully capable physiological monitoring and gating system to provide opportunities to undertake cardiac and respiratory gating which reduces motion burring to provide crisp anatomical images. Animals are anesthetized with a reliable gas delivery system and thermoregulation is provided during the imaging exam. A diverse set of MRI clinically translatable acquisition sequences can be selected by researchers for optimization of tissue contrast. The Core also provides MRI technical expertise to guide and assist researchers with selection of the optimal image acquisition approach and acquire images for investigators. Data analysis expertise is also available.

Bruker 7 Tesla

7T MRI

$250.00/hour*




The Center for Molecular Imaging maintains a Bruker 7 Tesla horizontal bore MRI scanner providing state-of-the-art instrumentation with a broad range of image acquisition capabilities. Full physiological monitoring and respiratory/cardiac gating capabilities are available. Animals may be anesthetized using injectable drugs or with a reliable gas delivery system. Thermoregulation is accomplished via a heated circulating water bath. Radiofrequency volume and surface coils are available, accommodating samples of many sizes and geometries. A state-of-the-art 4-channel quadrature CryoProbe is also available for mouse imaging which provides approximately a 2.5x-improvement in signal-to-noise. Clinically translatable acquisition sequences can be selected by researchers to optimize tissue contrast for their studies. MRI technical expertise is provided to guide and assist researchers with selection of the optimal image acquisition approach and acquire images for their individual research needs. Data analysis is performed using custom-developed software, commercial software, and software obtained from other research MRI centers.


IVIS Spectrum


Biolum / Fluoro

$150.00/hour


The IVIS® Spectrum in vivo imaging system uses a novel patented optical imaging technology to facilitate non-invasive longitudinal monitoring of disease progression, cell trafficking and gene expression patterns in living animals. The IVIS Spectrum is a versatile and advanced in vivo imaging system. An optimized set of high efficiency filters and spectral un-mixing algorithms lets you take full advantage of bioluminescent and fluorescent reporters across the blue to near infrared wavelength region. The system includes a highly sensitive camera, a dark imaging chamber to minimize incident light, and software to quantify the results. The IVIS imaging systems start with a back-thinned CCD camera, designed for high-efficiency photon detection, particularly in the important red region of the spectrum. It can detect very small numbers of photons as well as operate as a traditional camera; displaying images in that wide signal range is a function of the system's Living Image™ software. The CCD is cooled and the electronic readout is optimized so that the data gathered to create the real-time in vivo images have extremely low noise. Up to 5 animals can be imaged at a time and thermoregulation is achieved by means of a heated stage. Inhalable anesthesia is delivered via nose cones throughout the imaging procedure.

Bruker SkyScan


CT

$175.00/hour*


The SkyScan 1176 is a high performance in vivo micro CT scanner for preclinical research. The large format 11 megapixel x-ray camera gives an unrivalled combination of resolution, image field size and scan speed. Image field width up to 68 mm allows full body mouse and rat scanning. Variable x-ray applied voltage and filters provide scanning flexibility to allow imaging of a wide range of samples from lung tissue to bone. An integrated physiological monitoring subsystem provides breathing and heart-beat gating for proven thoracic image improvement by synchronized acquisition and a dedicated inhalable anesthesia system is in place.


Data Reconstruction

*Note - A $65.00 per appointment data reconstruction fee will be added to each MR imaging appointment.


Recharge Rates Approved by Office of Financial Analysis as of 10/01/2020